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PDF-MALDI Source 

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PDF-MALDI for fast offline analyses 

The Pulsed Dynamic Focusing MALDI (PDF-MALDI) source provides fast, easy, and ultrasensitive analysis for samples that do not need online separation. Paired with an Agilent 6300 Series Ion Trap LC/MS and Agilent’s powerful Spectrum Mill software, the PDF-MALDI source is ideal for fast analysis of 2D gel-spot digests. It provides clean, searchable MS/MS spectra at attomole levels. The PDF-MALDI source can also be paired with the Agilent 6200 Series Time-of-Flight LC/MS systems for protein identification and confirmation using peptide mass fingerprinting (PMF), or with Agilent 6500 Series Quadrupole Time-of-Flight LC/MS systems.
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Features
  • Pulsed dynamic focusing directs more sample ions from the MALDI target plate into the mass spectrometer and improving the sensitivity and consistency of the MS analysis
  • Heated drying gas directed onto the sample plate helps reduce the formation of matrix clusters, resulting in cleaner mass spectra
  • Improved camera optics give a clearer, wider view of the target plate and spots
  • A more precise target plate positioning mechanism facilitates accurate, automated data acquisition
  • Operates at atmospheric pressure so a target plate can be loaded in seconds — without tools
  • A more rugged design ensures repeatable alignment of the laser when replacing target plates or switching between the PDF-MALDI and other ion sources
  • Larger source body can accommodate Applied Biosystems/MDS SCIEX's 10 x 10 MALDI plates

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