Probe coverage characteristics on Agilent SurePrint G3 microarrays
Typical probe coverage characteristics on Agilent SurePrint G3 Human microarrays as illustrated using UCSC Human Genome Browser (hg 18, NCBI build 36, March 2006). The probe locations are shown at the bottom. Each vertical bar represents a single probe on the corresponding array.
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A 340 KB window on chromosome 17 showing comprehensive coverage over coding and non-coding regions. |
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A 600 KB window on chromosome 1 showing high-density coverage of a CNV region on the 2x400K CNV array.
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A 3 MB window showing the pseudoautosomal region on chromosome X.
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Enhanced Precision and Novel Detection on the Agilent SurePrint G3 Human CGH 1x1M microarray
Genomic variations include both gains and losses of chromosomal regions that often vary extensively in their sizes. The enhanced detection resolution enabled through the Agilent SurePrint G3 high-density microarrays delivers the highest precision in mapping chromosome breakpoints and identification of micro-variations that are not detected by other platforms.
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DNA Analytics views of Agilent SurePrint HD 244K and SurePrint G3 1 x 1M microarrays. Confirmation of a single probe call (arrow) on 244K microarray with a six probe call (~ 10 KB) on the SurePrint G3 1 x 1M microarray.
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Refinement of breakpoints (green arrows) and structure (orange arrows) in WWOX gene.
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