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Agilent 1200 Series Rapid Resolution LC system and the Agilent 6210 TOF MS - Highest data content with highest throughput
Abstract:
Fast and unambiguous determination of purity and identity of compounds
derived from screening libraries is a common task for many
analytical labs in the pharmaceutical industriy. The method of choice to
determine the identity of compounds is mass spectrometry, preferably
with accurate mass. As yet, data quality was usually compromised by
gaining higher throughput. This Application Note demonstrates how a
daily throughput of far more than 1000 samples can be achieved together
with full spectral data acquisition and accurate mass information with
close to FT-MS mass accuracy.
Keywords:
1200, 1200SL, 1200RRLC
RRHT, LC, liquid chromatography
Stablebond, SB, SB C18, 600 bar
Sub-2-micron, sub-two-micron sub-2u, sub-2µ, high throughput
LC/MS, LCMS
Chemical library, libraries
TOF, time-of-flight, 6210
accurate mass, Technology
Publication Number:
5989-4505EN
Last Updated:
11/2/2009
Number of Pages:
8
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(0.23 MB)