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Retention Time Locking: Concepts and Applications
Abstract:
The concepts and applications of retention time locking (RTL) are described. RTL simplifies the process of transferring methods from chromatographic instrument to chromatographic instrument, column to column, and detector to detector. The analysis of impurities in styrene according to ASTM D 5135 is used to demonstrate the efficacy of the approach. Using RTL, the retention times matched within an average of 0.16% (0.02-0.03 minute) in constant pressure mode.
Keywords:
retention time locking, RTL, method validation, styrene analysis, ASTM D 5135, capillary gas chromatography, laboratory productivity, Technology
Publication Number:
5966-2469E
Last Updated:
11/3/2009
Number of Pages:
8
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(0.29 MB)