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Agilent 1260 Infinity Analytical SFC System
Easy-to-use SFC system for superior resolution in chiral separations
Super critical fluid chromatography (SFC) is a seamless extension of conventional HPLC, offering an alternative and attractive separation technology for superior resolution of chiral compounds and trace analytes in pharmaceutical samples. SFC has many advantages over conventional HPLC such as significantly reduced consumption of organic solvent and ultrafast separation at moderate operating pressures using conventional particle size columns. The 1260 Infinity Analytical SFC system provides you with a breakthrough, tenfold increase in sensitivity compared to existing SFC solutions. The system comprises a modified 1260 Infinity Binary LC coupled to an Aurora SFC Fusion A5 module for conversion of gaseous CO
2
to the supercritical state.
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Features
Combined Aurora and Agilent solvent delivery system for delivery of CO
2
flow with same pulseless precision as for water and organic solvent
Dynamic range greater than 10,000 for measurement of enantiometric excess and quantification of impurities that are 0.1 percent of the main peak
Special high pressure SFC detector cell for superior sensitivity and low baseline noise
Ten- to fifteen fold lower operating costs by using standard grade gaseous CO
2
instead of highly expensive SFC grade liquidified CO
2
High separation efficiency through low mobile phase viscosity and better diffusion characteristics
Wide range of organic modifiers for expanded selectivity
Fast, straightforward method development and rapid column equilibration
Low solvent consumption and less waste generation for true green chemistry
Flow rates up to 5 mL/min
System delay volumes optimized for fast chromatography
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1260 Infinity Binary LC system
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