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1260 Infinity Analytical SFC System

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1260 Infinity Analytical SFC System 
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Product Description
The 1260 Infinity Analytical SFC system is an easy-to-use SFC system for chiral and a-chiral separations, providing LC-like sensitivity and UHPLC power range. Unique SFC/UHPLC switching capability with the SFC/UHPLC Hybrid system provides two orthogonal separation modes in one single system. This enables intelligent screening for the best suitable method and delivers comprehensive information for complex samples and impurity analysis. The Agilent 1260 SFC solution include the broadest and most versatile SFC price/performance range - from simple SFC upgrades to pre-existing 1100/1200/1260 LC systems to full SFC/UHPLC/MS solutions.
 
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Typical performance of the 1260 Infinity Analytical SFC system
 
Important information for customers of Aurora SFC Systems
  • Available as complete system or as upgrade to existing Agilent 1100, 1200 and 1260 LC systems
  • Unique switching capability between UHPLC/SFC in a single system without equilibration
  • Only SFC system with 600 bar capability
  • Different solvent selection choices for a wide range of organic modifiers to exploit unique selectivity
  • UHPLC-like sensitivity
  • Ten - to fifteen fold lower operating costs by using standard grade gaseous CO2
  • Optional full method development features available for fast, straightforward column and modifier selection
  • MS compatibility with the Agilent 6100 Series Single Quadrupole LC/MS systems
  • Low solvent consumption and less waste generation for true green chemistry
  • Agilent instrument and service quality
  • Ordering Details

    • Feature

    Specification

    System

     

    Flow range

    0.1 mL/min to 5 mL/min (settable), 1 mL to 5 mL/min recommended

    Maximum operating pressure

    600 bar

    Upgrade possibility of existing 1100/ 1200 / 1260 LC

    yes

    Option for SFC/ UHPLC in one system

    yes

    CO2 purity requirements

    99.99% for gas, 99.999% for liquid

    Unattended operation

    Leak sensors, diagnostic software features

    Fusion A5 SFC Module

     

    backpressure accuracy

    +/- 1%

    Backpressure precision

    +/- 0.5 bar (+/-0.2 bar typical)

    Backpressure thermal precision

    +/- 1C

    Chiller temperature

    -20C to  9 C

    Pump

     

    Number of co-solvents

    1, with SSV pump option 3, with external SSV 12

    Precision of flow rate

     Same as G1312B, ≤0.07 % RSD or ≤0.02 min SD, whatever is greater based on retention time at

    constant room temperature

    Precision of composition

    Same  As G1312B, < 0.15 % RSD or < 0.04 min SD whatever

    is greater

    Autosampler

     

    Number of samples

    100 x 2 mL vials, 30 x 6 mL vials

    Injection volume

    5 uL for  full loop injections (5 uL loop as default) larger loops possible (10uL), partial loop filling for smaller injection volumes

    Injection principle

    Fixed loop

    Injection precision

    <0.3% RSD for 5 ul

    Sample temperature control

    4-40C with sample thermostat

    Sample carryover

    0.05%

    Column compartment (TCC)

     

    Column

    Up to 300 mm length x 4.6 mm ID (or less)

    Column capacity

    Up to 3, with additional 2x TCCs up to 9

    Switching valve

    Optional (2/6, 2/10, 8/9, 6 column selector)

    Temperature range

    Ambient -10C to 100 C

    Column compartement temperature accuracy

    +/- 0.5C

    Column compartement temperature stability

    +/- 0.05C

    Active solvent pre-heating and post-conditioning

    As standard

    Automated Method development

    optional

    Detector

     

    Wave length range

    190-950 nm

    Wavelenghth accuracy

    +/- 1 nm

    Linearity range

    2.0 AU @ 265 nm

    Noise, wet

    +/- 0.05 mAU under SFC conditions at 254 nm 20% MetOH/80% CO2

    +/- 0.007 mAU under LC condition

    Drift

    0.9 mAU/hr

    Data rate

    80 Hz

    Cell pressure limit

    400 bar

    Cell path length

    10 mm

    Cell volume

    13 ul

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