Over the coming months, the American Recovery and Reinvestment Act (ARRA) will provide hundreds of millions of dollars to researchers. To help you secure this funding quickly, Agilent would like to provide you with the necessary technical and financial details to include an Agilent platform in your grant application.
Agilent is also pleased to announce our Stimulus Grant Program. If you are applying for a grant from the ARRA, or have recently been awarded stimulus money, Agilent can provide further stimulus and reduce your system purchase price from $5,000 - $50,000 or more. Contact us to learn more about the Agilent Stimulus Grant Program and for a customized letter of justification, configuration and quote, and personalized letter of support for your grant application.
Below you will find some application- and instrument-specific information to help you get started with your grant application.
Genomics
Metabolomics
Proteomics
Water
Forensics & Toxicology
Biofuels
GENOMICS
This guide offers an overview of Agilent’s microarray and SureSelect product offerings with ordering details to assist researchers with the details of grant submission.
Specific to NIH grants, these instrument grant support packages provide an executive overview, letter of support, declaration of feature uniqueness, special promotions, and supporting literature.
METABOLOMICS
LC/MS for Discovery Metabolomics
Using the power of True Hi-Def TOF technology, the Agilent 6520 Accurate-Mass Q-TOF is a high sensitivity, highly reproducible solution optimized to find as many metabolites as possible in every sample for profiling studies.
With an unmatched combination of mass accuracy, mass resolution and in-spectrum dynamic range, the 6520 Q-TOF with the Agilent METLIN Personal Metabolite Database facilitates structural elucidation and identification of target metabolites.
Using Agilent GeneSpring MS software, easily import, normalize and compare data from large sample sets with metadata as well as find relationships in complex experimental designs beyond pair-wise comparison.
Contact us for a customized letter of justification, configuration and quote, and personalized letter of support for your grant application.
LC/MS for Targeted Metabolomics
The Agilent LC/MS Targeted Metabolomics System consists of a 6460 Triple Quad LC/MS system which combines industry-leading femtogram-level sensitivity and accurate quantitation with exceptional reliability. The result is a solution that consistently delivers both superior analytical capabilities, as well as the throughput required to process large sample sets.
MassHunter software automatically produces a quantitation report for import into GeneSpring MS for statistical analysis. GeneSpring MS supports metadata analysis and helps you find relationships in complex experimental designs.
By integrating the instruments, columns and software this solution ensures maximum performance even at maximum throughput, resulting in the lowest cost per sample.
Contact us for a customized letter of justification, configuration and quote, and personalized letter of support for your grant application.
GC/MS for Discovery or Targeted Metabolomics (value package)
Agilent’s Single Quadrupole GC/MS Metabolomics solution couples the popular Agilent 7890A GC with the innovative 5975C GC/MSD to deliver an unbeatable combination of performance, reliability and cost-effectiveness for routine profiling studies. This system generates high quality, library searchable EI spectra and enables the confident identification of targets using the Agilent Fiehn Metabolomics Library, the only commercially available database for metabolomics.
The Agilent GC/MS Metabolomics Retention Time standards kit provides a convenient, complete set of chemicals for retention time locking of the Agilent Fiehn method as well as internal standards to track GC/MS system performance.
Using Agilent GeneSpring MS software, easily import, normalize and compare data from large sample sets with metadata as well as find relationships in complex experimental designs beyond pair-wise comparison.
Contact us for a customized letter of justification, configuration and quote, and personalized letter of support for your grant application.
GC/MS for Discovery or Targeted Metabolomics (premier package)
Where targeted metabolomics require the very lowest levels of detection and quantification of extremely low abundance metabolites, Agilent’s 7000A Triple Quadrupole GC/MS system combines unmatched sensitivity and selectivity with everyday reliability and ease of use. This system generates high quality, library searchable EI spectra and enables the confident identification of targets using the Agilent Fiehn Metabolomics Library, the only commercially available database for metabolomics.
The Agilent GC/MS Metabolomics Retention Time standards kit provides a convenient, complete set of chemicals for retention time locking of the Agilent Fiehn method as well as internal standards to track GC/MS system performance. For unknown metabolites, MS/MS capability allows for the interpretation of spectra to identify compounds not in the spectral databases.
Using Agilent GeneSpring MS software, easily import, normalize and compare data from large sample sets with metadata as well as find relationships in complex experimental designs beyond pair-wise comparison.
Contact us for a customized letter of justification, configuration and quote, and personalized letter of support for your grant application.
PROTEOMICS
LC/MS for Biomarker Discovery
Protein biomarkers are usually present at low levels and within complex mixtures. Biomarker discovery presents both sample preparation and detection challenges. The Agilent HPLC-Chip and 6520 Accurate Mass Q-TOF couple high performance chromatography with fast scanning and highly specific mass spectrometry. GeneSpring MS software enables comparison of complex samples to find potential markers. Accurate mass MS/MS with high scan frequency enables a lower false positive rate for more confident protein ID.
Contact us for a customized letter of justification, configuration and quote, and personalized letter of support for your grant application.
LC/MS for Protein Identification
Because proteins of interest are typically present at very low abundance, the analytical methods must also be extremely sensitive. The Agilent HPLC-Chip and 6520 Accurate Mass Q-TOF couple high performance chromatography with fast scanning and highly specific mass spectrometry. Accurate mass MS/MS with high scan frequency enables a lower false positive rate for more confident protein ID.
Contact us for a customized letter of justification, configuration and quote, and personalized letter of support for your grant application.
LC/MS for Protein Quantitation
For complete elucidation of biological mechanisms, proteins are now required to be accurately and routinely quantified. For accurate, high-throughput “absolute” quantitation, the Agilent HPLC-Chip and 6410 Triple Quad LC/MS system provides targeted MRM peptide quantitation at femtogram detection levels, as well as the necessary throughput and 24/7 day-after-day reliability.
Contact us for a customized letter of justification, configuration and quote, and personalized letter of support for your grant application.
WATER
LC/MS and GC/MS for Water Research
Modern problems in the water industry are concerned with a range of new problems from recycled water to aging infrastructure to emerging pollutants like pharmaceuticals (PPCP) and Endocrine disruptor compounds (EDCs). For many of these new compounds the best treatment strategy is still in development. Academic, water utility and government labs need the best technology to solve these problems.
Agilent tools are just what is needed to solve nearly every problem from pollutant breakdown during treatment (TOF and Q-TOF) to low level determinations in clean water (LC Triple Quadrupole MS and GC Triple Quadrupole MS). Where the Agilent solutions really do well is when matrix problems become an issue for trace determinations. In this case the chromatographic front end to the MS spectrometer is second to none in terms of resolving the peaks of interest from interferences and also speeding the analysis to meet the productivity requirements of every lab.
Agilent has excellent collaborations in the areas of perflorinated organics and pharmaceuticals in water, the US EPA and University of Colorado respectively, so we have the right experience and tools to solve real problems at the edge of this science.
Contact us for a customized letter of justification, configuration and quote, and personalized letter of support for your grant application.
ICP-MS for Water Research and Production
The worlds water infrastructure is too old, falling apart and lacks the capacity to meet world demand. Significant government and academic dollars are being allocated and spent to address these problems. Agilent’s solutions for metals analysis are second to none and you should remember them as you approach academic water research labs, often found in the departments of civil engineering at leading universities but especially those in land grant institutions. Government labs and municipal and regional water supplier research labs are also prime targets.
While some problems, such as lead analysis, are obvious and relatively trivial for the Agilent 7500 Series ICP-MS, other problems, such as siloxane buildup from biogas use at water treatment plants are less obvious. The Agilent solution, using hyphenated GC-ICP-MS is a proven winner for monitoring and understanding this problem.
Contact us for a customized letter of justification, configuration and quote, and personalized letter of support for your grant application.
FORENSICS & TOXICOLOGY
GC/MS & LC/MS for Forensics and Toxicology
From screening to confirmation, Agilent’s broad portfolio of LC/MS and GC/MS instruments deliver the evidentiary data quality you require with the productivity you demand! Rapid, flexible screening for unknowns is now routine with the Agilent 6200 series LC/TOF/MS and the new Forensic & Toxicology Accurate Mass Database. You get “all the data, all the time” for comprehensive identification of every sample component - even those not on your target list. Or consider the 6500 Series QTOF to add the benefits of MS/MS confirmation. Thinking of adopting LC/QQQ for targeted screening or confirmation? Then the Agilent 6400 LC/QQQ is right for you!
GC/MS has long been the gold standard for confirmatory analysis and Agilent has been at the forefront with its legendary reliability and performance. This tradition continues with the 5975C Series GC/MSD system. The patented Capillary Flow Technology reduces scheduled downtime for system maintenance, reduces the overall analysis cycle time, and even provides the capability for orthogonal detection for enhanced data quality.
In addition, Agilent’s Deconvolution Reporting Software and Forensic & Toxicology database dramatically reduces the complexity and time required for data interpretation. And now the new 7000A Triple Quadrupole GC/MS extends the Agilent legacy for those applications requiring superior detection capability such as the analysis of steroids or alternative matrix samples.
Contact us for a customized letter of justification, configuration and quote, and personalized letter of support for your grant application.
BIOFUELS
GC/MS & LC/MS for Biofuels
Unraveling the chemistry and optimal conditions for extracting fuels from biomass requires sorting through countless compounds, often in a complex matrix, to identify and quantitatively measure those intermediates that lead to commercially viable processes. Agilent’s broad portfolio of LC/MS and GC/MS instruments allows the researcher to select the perfect tool for this task regardless of their specific area of interest. As the world leader in separation science, Agilent has the right product, the technical expertise, and the industry experience to unequivocally provide the data and service that you need to make the decisions to guide your experiments to a successful conclusion.
Agilent’s 7890A Gas Chromatograph with our patented Capillary Flow Technology provides unmatched control over the chromatographic separation with the added benefit of reduced downtime for system maintenance and reduced analysis cycle time. For liquid separations, the 1200 RRLC continues as the workhorse for most liquid chromatography applications while those with the most challenging requirements can choose the recently introduced 1290 Infinity UHPLC that is the new gold standard for power and performance in liquid chromatography. Combine these with one of our mass spectroscopy platforms for unparallel performance and productivity. And, the MassHunter software makes both operation and interpretation easy and reliable for the non-specialist.
Need help in selection of the best technique?
For LC-MS options: 6400 Series Triple Quadrupole LC/MS
For GC-MS options, check out the basic 5975C Series GC/MSD or the premium 7000A Triple Quadrupole GC/MS
Contact us for a customized letter of justification, configuration and quote, and personalized letter of support for your grant application.