KB005438: Creating experiment by using .xls file with Affymetrix Chips and loading the .xls file into GeneSpring GX 

A. GeneSpring GX10 supports Affymetrix CEL and CHP files as standard format. The other file formats supported such as .txt, .xls, .tsv and .csv.

You could work with .xls file by ‘Creating a Custom Technology’. To create a custom technology, follow the steps below:

1. Go to Annotations in the Menu bar -> Create Technology -> Custom from File
2. After creating the custom technology, you could create the experiment under ‘Generic Single color’ Experiment Type.

For more details please refer Chapter 15 & 16 on ‘Custom Technology Creation’ from the GeneSpring Manual.