Software Status Bulletin

G3793AA MassHunter Software rev. B.02.00

Revision Log:

Revision Date	Reason For Update
08/28/2008	Final release for B.01.04 revision (compatibility for MassHunter QQQ Acquisition B.01.04 Patch 1- 6410 only)
11/11/2008	Final release for B.02.00 revision (compatible for MassHunter QQQ Acquisition B.02.00 for 6460 and B.02.01 for 6410/6460)

1. Overview

The purpose of this document is to list known problems in the software and any known workarounds or recovery paths.

2. Known Problem Summary

The following is a summary of the known problems in the software. This is not an exhaustive list, but is a list of the problems a customer is most likely to encounter. This list cross-references items in our Defect tracking database.

SCR #	Title
12866	MassHunter Workstation Acquisition can be closed while MassHunter Optimizer is running.
12876	“Optimization complete” message may be hidden.
13201	Compound Browser Formula requires exact syntax and spaces to reference in table.
13328	MassHunter Optimizer changes default method folder in MassHunter Acquisition.
13679	“SaveAsProject” cannot overwrite as default.
13703	“All records” progress bar does not work accurately.
13840	Compound Setup Table does not maintain the order of each row when saved.
13882	Project must be saved first to see the Summary Results View
14119	G1367D ALS SL+ may have Invalid Plate Positions – B.02.00
14122	Some Project Information Settings are Lost when upgrading (B.02.00 from B.01.04)
14187	Deleting Project Information may not be Complete.

3. Known Problems Detailed Description

The following is the detailed descriptions of the known problems in the MassHunter Optimizer software. This section includes more extensive information from our defect tracking database. This section also includes any known workarounds or recovery paths

SCR #12866
Title	MassHunter Workstation Acquisition can be closed while MassHunter Optimizer is running.
Description	One can inadvertently close MassHunter Workstation Acquisition while MassHunter Optimizer is running. There are no warnings or error messages, and Optimizer stops and needs to close.

SCR 12876
Title	“Optimization complete” message may be hidden.
Description	There is an “Optimization complete” pop up message that may be behind other open applications. In this case, the message is hidden, can be toggled to view, and then close.

SCR 13201
Title	Compound Browser Formula requires exact syntax and spaces to reference in table.
Description	In the Compound Browser, select Search Compounds/Formula and then enter a valid formula for a compound optimized. For example, use C66H95O26N1 which should reference the [Glu] fibrinopeptide b that had been optimized previously and now part of the database. Instead, spaces are required to correctly reference as C66 H95 O26 N19. How the compound was entered is how it will be referenced in the browser.
Workaround	Use exact syntax and spacing as entered to reference Compound Browser correctly

SCR #13328
Title	MassHunter Optimizer changes default method folder in MassHunter Acquisition.
Description	After running and closing MassHunter Optimizer, load a method in MassHunter. The default folder location is no longer D:\MassHunter\methods.
Workaround	Re-establish the method folder path by navigating to D:\MassHunter\methods.

SCR #13679
Title	“SaveAsProject” cannot overwrite as default.
Description	MassHunter Optimizer “SaveAsProject” cannot overwrite an existing project file name.
Workaround	“SaveAsProject” to a new project file name.

SCR #13703
Title	“All records” progress bar does not work accurately.
Description	While running MassHunter Optimizer, the “All records” progress bar (the second one on the bottom) does not update its status as expected.

SCR #13840
Title	Compound Setup Table does not maintain the order of each row when saved.
Description	Save a project after adding/importing some records with result in the Compound Setup tab (i.e.: Add CompoundRow, MethodRows, PrecursorIonRow, and ProductIonRows) and then close. Open the project again shows the order of each row of the Compound Table is not as it was when last saved.

SCR #13882
Title	Project must be saved first to see the Summary Results View.
Description	When the results are ready after optimization, the Summary Results View shows up empty (blank) unless project is saved first.
Workaround	Save project first to see Summary Results View.

SCR #14119
Title	G1367D ALS SL+ may have Invalid Plate Positions – B.02.00
Description	When using the newer G1367D ALS SL+ sampler, the plate positions may be invalid.
Workaround	Downgrade the firmware on the G1367D LC module to 6.10 and configure as a G1367C temporarily.

SCR #14122
Title	Some Project Information Settings are Lost when upgrading (B.02.00 from B.01.04)
Description	When upgrading from B.01.04 to B.02.00 on 6410 Triple Quad LC/MS systems, some project information settings like all selected compound list, fine fragmentor, and etc. are lost.

SCR #14187
Title	Deleting Project Information may not be Complete.
Description	When deleting project information such as a product ion row and then saved, the information may still be visible after re-loading the project. This only occurs at first start up when the database is empty and for 1 project with 1 compound.

Appendix A. Glossary

Term / Acronym	Definition
UI	User Interface. The visual representation of the software with which a user interacts.