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A New Design of Ion lens and Collision Reaction Cell for High-Efficiency Collision Mode Interference Removal for ICP-MS.

Abstract: The rapid acceptance of collision/reaction cells in quadrupole ICP-MS is indicative of the contribution that this technology can make to improving analytical accuracy and the reliability of ICP-MS data, especially for the traditionally “difficult” analytes, which suffer from polyatomic interferences in some sample matrices. Since the development of collision/reaction cells in ICP-MS, the relative performance of collision and reaction processes has been debated. The conclusion is that reactive cell gases may provide efficient removal of some interferences, but they are not suitable for the removal of multiple interferences on multiple elements and, since the removal process is dependent on the reactivity of the interference, reactive cell gases are not suitable for unknown or variable interferences, whereas collisional interference removal is.

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