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Agilent 1200 Series LC Method Development Solution - Automated method development with up to eight columns

Abstract: The Agilent 1200 Series LC Method Development Solution offers a highly flexible system that can be used for up to eight columns up to 100 mm in length and up to six columns with lengths of up to 300 mm. Several independent heated zones are available to optimize the temperature for different columns. In this Technical Note, we will describe how valves, capillaries, columns, and solvent selection valve are integrated into an Agilent 1200 Series Rapid Resolution LC (RRLC) system; how to set up a method development system in Agilent ChemStation; an application example using six different columns; and comparison of performance with a standard Agilent 1200 Series RRLC system using columns with 3.0 and 2.1 mm internal diameters on both.

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