Agilent | BIO-DIS III (Apparatus 3)

Flexible and easily configured to meet your testing needs

The Agilent BIO-DIS III Extended Release Testing Station is ideal for automatic dissolution profiling of extended release dosage forms requiring USP Apparatus 3 and EP reciprocating cylinder specifications. Capable of running unattended for periods of up to six days, the unit can store up to 15 programs and provide direct control over time points, agitation rate, sampling rate, movement between vessel rows, hold dip, and drain times. The BIO-DIS transports the dosage form from one row of media to the next, allowing a simulated pH change.

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Biorelevant. Simulate gastrointestinal conditions with simple programming that allows in vitro dissolution pH profiling with biorelevant agitation rates and retention times
Flexible. Use one instrument to test and transport a variety of samples, saving valuable bench space. Samples are automatically transported from one medium to the next without operator intervention
Optional Temperature Control. Maintain temperature with the optional 750D Heater/Circulator. All parameters are controlled by the BIO-DIS III and entered from the front panel keypad
Easily configured. Select a standard volumetric reciprocating cylinder option, or small and large volume configuration to meet testing needs for low dose or poorly soluble formulations
Automated Sampling. Easily perform automated sampling by integrating the Agilent 8000 Dissolution Sampling Station
Reporting. The built-in Report Center Printer provides hard-copy documentation of testing progress and conditions. The four-line digital display provides updated operation information as the test progresses
Compliant. Be confident knowing the BIO-DIS is compliant with the reciprocating cylinder apparatus, USP Apparatus 3 and EP harmonized specifications
Software Control is available through the 21 CFR compliant Dissolution Workstation Software which allows direct programming of the BIO-DIS III and 8000 Sampling Station along with various pumps and filter changer

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Dissolution Workstation Software

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