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6400 Series Triple Quadrupole LC/MS 

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6490 with iFunnel technology, attograms limits of detection, and zeptomole sensitivity 
Unprecedented sensitivity and value 
Whether you are quantifying pharmaceutical candidates, measuring trace-level environmental or food contaminants, or confirming biomarkers, the Agilent 6400 Series Triple Quadrupole LC/MS Systems offer greater sensitivity, productivity, and value than ever before. The new 6490 with breakthrough iFunnel technology provides maximum sensitivity—attograms limits of detection and zeptomole sensitivity with an unprecedented six logs of linearity. Or choose the 6430 Triple Quad with 30 ms polarity switching and a sensitivity range between the 6460 and 6420 with femtogram-level limits of detection, Agilent reliability, and lab-friendly ease-of-use.
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Features
  • iFunnel technology – dramatically increases the number of ions that enter the mass spectrometer, enabling zeptomole sensitivity for your most demanding analyses
  • Newest Portfolio of LC Triple Quads – Agilent has introduced a new Triple Quad every year for the last four years.  The 6420, 6430, 6460 and 6490 Triple Quads all offer robust solutions for busy laboratories. The sensitivity of this portfolio increases fifty fold from the 6420 to the top-of-the-line 6490.
  • Innovative, Dynamic Multiple Reaction Monitoring (MRM) – simplifies method development and ensures consistent ion statistics with constant cycle times resulting in greater reproducibility than other methods for peak area measurements
  • Triggered MRM – combines MRM quantitative analysis with the generation of a product ion spectrum.  This spectrum may be used for library searching and compound confirmation.

  • MassHunter MS Optimizer software – automatically optimizes ion transitions and fragmentor and collision energies for both singly charged small molecules and multiply charged peptides

  • High-throughput analyses – the Agilent version of the popular CTC autosampler with sample capacities up to 36 plates

  • MassHunter Quantitative Analysis software – compound- and sample-centric with unique features like a parameterless integrator that helps you reduce mass spectrometry data to meaningful quantitative results with minimal manual intervention

  • Fully customizable reports – enable better-informed and more collaborative decision making

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