Descriptions and specifications supersede all previous information and are subject to change without notice.
| Mass range, mass resolution, and scan speed |
 |
6310 |
6320, 6330, and 6340 |
Mass Range
m/z |
Resolution
FWHM (u) |
Scan Speed
(u/s) |
Resolution
FWHM (u) |
Scan Speed*
(u/s) |
| 50 - 2200 |
≤ 0.6 |
13,000 |
≤ 0.6 |
26,000 |
| ≤ 0.45 |
5,500 |
≤ 0.35 |
8,100 |
| ≤ 0.35 |
1,650 |
≤ 0.25 |
800 |
| 200 - 4000 |
3 - 4 |
27,000 |
≤ 3 |
27,000 |
*Total scan cycle times for the 6330 and 6340 are approximately 1/3 the scan cycle time of the 6320, allowing the 6330 and 6340 to perform 3X as many scans at the same nominal scan speed. In the 6340, ETD and ETD+CID operating modes increase scan cycle times slightly compared to CID-only operation. Mass Accuracy (All)
±0.2 u within the calibrated standard mass range at normal resolution in full scan mode,
with proper calibration, ICC target and ion statistics, and thermal equilibrium of electronics
and ion source. Mass Axis Stability (All)
Within ±0.2 u of the observed calibrated value over 8 hours in standard mass range
at normal resolution in full scan mode, with proper ICC target and ion statistics,
and thermal equilibrium of electronics and ion source and ambient temperature of 21°C ± 3°C (70°F ± 6°F). Monoisotopic Precursor Selection (All)
Monoisotopic precursor selection is possible throughout the standard mass range (m/z 50 - 2200) at an ambient temperature of 21°C ± 3°C (70°F ± 6°F). Polarity Switching
6310 ˜ 0.5 seconds
6320 ˜ 0.5 seconds
6330 ˜ 0.5 seconds
6340 ˜ 0.5 seconds Sensitivity Specification
Conditions Column – ZORBAX Rapid Resolution SB-C18 2.1×30 mm 3.5 micron
Mobile Phase – 25% water 75% methanol 5 mM ammonium acetate
Flow rate – 400 µl/min (200 µl/min for XCT)
Mode – full scan MS/MS
MS/MS – transition of the protonated molecular ion (m/z 609) to the sum
of the two most abundant product ions
Product ion scan range – m/z 175 - 650
Mass range – standard (m/z 50 - 2200)
Resolution – normal/ultrascan (0.6 u)
| Sensitivity |
|
6310 |
6320 |
6330 |
6340 |
| Quantity (reserpine - on column) |
5 pg |
1 pg |
250 fg |
TBD* |
| Signal-to-Noise Ratio (full scan MS/MS) |
≥ 25:1 |
≥ 50:1 |
≥ 50:1 |
TBD* | *TBD - To be determined
Stages of MS
| Stages of MS |
|
Automated |
Manual |
| 6310 |
5 |
11 |
| 6320 |
5 |
11 |
| 6330 |
5 |
11 |
| 6340 |
5 |
11 |
Descriptions and specifications supersede all previous information and are subject to change without notice.
|