Peptide Mapping
Significant success has been realized for peptide mapping by CZE and CZE/MS. In peptide mapping a protein is enzymatically or chemically cleaved into smaller peptide fragments and subsequently separated. The analysis is primarily qualitative and is used to detect subtle differences in proteins. CZE and CE/MS is very useful as a second-dimension analysis of HPLC-purified peptides.
 Application Literature
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