Cell-Based Screening
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An automated, high-throughput, cell-based screening assay using Molecular Devices FLIPR and Calcium-3 Kit to measure calcium flux.
The GPCR family is a very important target area for Drug Discovery, and many of those targets can be assayed via intracellular calcium measurement. The FLIPR, and especially the new FLIPRTetra from Molecular Devices, is designed to perform this measurement in a reliable and effective manner ... read entire application note. |
Compound Management
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This BioCel links into your LIMS for receiving and delivering inventory information, keeping both the BioCel database and your sample inventory synchronized and up-to-date.
In compound handling, sample inventory and sample integrity are the keys to success. Flexibility in plate format and liquid handling options allow the simultaneous use of 384- and 1536-well plates as the source or destination, accommodating volume transfers from 2.5 nL to 50 μL. This BioCel system is a dual robot system, with a variety of liquid handling options ... read entire application note. |
Enzymatic Screening
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This BioCel System performs a high-throughput, bioluminescent antibody-independent kinase assay utilizing 1536-well microplates ... read entire application note. |
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This flexible, high-throughput BioCel System includes high quality liquid handlers, readers, and an active environmental control, ideally suited for enzymatic screening.
A multimode reader (Zeiss Plate::Vision), bulk reagent dispensers (Genetix QFill2, Aliquot), plate washer (Bio-Tek ELx405 Select), and the Agilent Vertical Pipetting Station allow assays to be run in 96-, 384-, or 1536-format. In combination with the multimode reader, a variety of detection modes are used: FI, FP, TRF, and absorbance. The active environmental control allows assays to be run at constant temperature (ambient up to 37°C), avoiding edge effects often caused by transport into and out of incubators ... read entire application note. |
Microplate Replication and Reformatting
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A compact, high-throughput bench top microplate replication solution.
The BenchCel Microplate Handler, integrated with the Bravo Automated Liquid Handling platform, provides a benchtop solution that can create 250 replicates from 50 source plates in only 3 hours. This system delivers an intelligent and scalable workflow, allowing for increased capacity and throughput with additional stacks or BenchCel Microplate Handlers ... read entire application note. |
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The integration of the Bravo Automated Liquid Handling Platform to the TTP comPILER allows for a comprehensive solution for the generation of assay plates and replicates from samples stored in comPOUND storage systems.
The addition of the BenchCel Workstation, PlateLoc Thermal Microplate Sealer and Microplate Labeler, provide a complete walk-away solution for compound management. The integration of Agilent VWorks with TTP Labtech’s control software allows researchers to request a variety of assay plates to be processed from stored compounds without user intervention ... read entire application note. |
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This BioCel System design gives the flexibility in microplate format and liquid handling, providing a throughput of a million compounds a day ... read entire application note. |
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This BioCel System handles compounds stored in a variety of formats-Matrix 96 tube racks and 384 microtube racks, as well as standard microplates.
With this BioCel, the world of tubes (compounds) merges smoothly with the world of plates (assays). A high storage capacity for plates (17 Agilent Labware Stackers, 900 plates) and tube racks (3 random access carousels, 288 racks) allow the production of several sets of assay plates from compound tubes. The speed of the BioCel robotic arm allows the system to process its full plate capacity in less than 8 hours ... read entire application note. |
Sample Picking
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The BenchCel Workstation with the LabCyte Echo Acoustic Dispenser and multiple microplate management instruments creates the most compact automated benchtop workstation for sample picking and dilution.
The Agilent LabCyte Echo based Hit picking Workstation was developed to provide a cost effective, automated hit picking solution for compound inventory management. With Agilent VWorks Automation Control software, the user has the ability to use LabCyte’s built-in Cherry Picking and Dose Response applications, or use VWorks scheduling tasks to create a customized workflow ... read entire application note. | |
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