Cell Biology Applications 

An automated Cytochrome P450 Assay from Agilent Technologies using the Bravo Liquid Handling Platform and the Promega P450-Glo.

This approach provides a reliable and efficient solution for quantifying Cytochrome P450 activity. Utilizing the plate stacking capabilities of the Bravo Platform, up to five plates can be run without user intervention. This instrument can easily scale to meet increasing capacity demands with the  integration of an Agilent BenchCel Microplate Handling Workstation ... read entire application note.

An automated high-throughput Cytochrome P450 assay using the Agilent BioCel 900 System.

The Agilent BioCel 900 System provides a robust high-throughput solution for quantifying Cytochrome P450 activity. The small footprint and open-access of the BioCel System makes it an ideal solution for medium to high- throughput ADME/Tox applications, such as the CYP450 assay outlined here. All microplates are handled and processed in the same manner, including constant incubation times, ensuring reliable and repeatable results ... read entire application note.

An automated, small footprint cell viability assay using the Agilent BenchCel Workstation and the Promega CellTiter-Glo Kit.

The Agilent Cell Viability Workstation using the Promega CellTiter-Glo kit provides a reliable high-throughput solution for analyzing cell viability. The integration of microplate handling, liquid handling, and microplate reading enables up to 65 microplates to be processed in one run without user intervention ... read entire application note.

An automated high-throughput cell-based assay using Molecular Devices FLIPR and Calcium-3 Kit to measure calcium flux.

The GPCR family is a very important target area for Drug Discovery, and many of those targets can be assayed via intracellular calcium measurement. The FLIPR, and especially the new FLIPRTetra from Molecular Devices, is designed to perform this measurement in a reliable and effective manner. The speed and versatility of its scheduling software makes Agilent’s BioCel System a perfect match for the FLIPRTetra ... read entire application note.

An automated, small footprint cell viability assay using the Agilent BenchCel Workstation, the Bravo Liquid Handling Platform, and the Promega CellTiter-Glo Kit.

The versatile Bravo Automated Liquid Handling Platform performs cooled or room temperature media exchange, thermal shaking, and cell plating. Precision control of the Bravo Platform and BenchCel Workstation guarantees gentle handling of cell cultures. Integration of incubators with CO2 control and industry-leading plate readers enables maximum throughput and walk-away time. The compact workstations can be integrated into a variety of enclosures to protect cultures from contamination ... read entire application note.