 Accurate mass measurement and empirical formula calculation for identification of unknown compounds by ESI-TOF mass spectrometry
Accurate mass measurement provides an extra measure of confidence in your analytical results by the confirmation of your identified compound. Whether you are screening the products of synthetic chemistry, analyzing metabolites, natural products or detecting minor impurities, the Agilent LC/MSD time-of-flight (TOF) mass spectrometer combines the power of accurate mass measurements in the lower single digit ppm with the ease of use of use of a quadrupole mass spectrometer to make accurate mass measurements routine.
Applications
- "Structure elucidation of degradation products of the anibiotic drug amoxicillin Part 2: Identification and confirmation by accurate mass measurement with ESI TOF of the compound ions and the fragments after CID" Click here to view.
More applications and technical principles are summarized in the Agilent compendium "TOF solutions in pharmaceutical development" Click here to view. |