“Do it Faster: Introducing the NEW 1200 Series LC Systems”
Doug McIntyre
Senior Application Scientist

How do you follow the most successful HPLC System in the world? The 1200 Series LC is the successor to the Agilent 1100. It’s reverse compatible with 1100 but offers even higher performance and ruggedness. The 1200 is composed of all the current LC modules and an entirely new system, call the Rapid Resolution System. With this introduction, Agilent offers the highest performance modules – capable of covering nano application through semi-prep. Additionally with the new RRLC system, you now can push your methods to 20x the speed and up to 60% more resolutions, taking advantage of the wide range of sub-two micron particle size columns in the Zorbax HT line. Can you take advantage of this technology? This talk will show you what’s new and how you can migrate your lab to more performance.

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“Transform your Lab: Introducing the NEW 6000 Series LC/MS System”
Rick Carberry
Sr. Director, LC/MS Marketing

The Agilent 6000 Series of LC/MS systems now includes a NEW triple quadrupole and QTOF instruments, as well as new models of Agilent’s single quadrupole, Ion Trap, and TOF mass spectrometers. The 6000 Series brings new levels of performance to LC/MS, and is uniquely differentiated by providing a reliability and ease of use not found in current LC/MS systems from other vendors. Proprietary technologies in hardware and application-specific software bring both state of the art performance and maximum productivity to your laboratory.

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Technical Breakout Session # 1- Pharmaceutical and Biotechnology Topics

Talk 1: “Protein Profiling, Identification and Biomarker Discovery using HPLC-Chip/QTOF”
Ning Tang
Senior Application Scientist

A new approach using profiling with an MS-only TOF, followed by data directed MS/MS with an ion trap is gaining interest from many researchers. Using the new Agilent 6510 QTOF this approach can be accomplished on a single instrument with high sensitivity HPLC-chip making it the ideal platform for Biomarker Discovery.

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Talk 2: “Metabolomic Profiling using new High Pressure LC/TOF”
Steve Fischer
Senior Application Scientist

Metabolomic profiling is used to screen and subsequently identify metabolites in complex samples such as urine and serum. Due the broad chemical variety of the analytes, the combination of the Agilent Multimode source with simultaneous ESI/APCI ionization, the new Agilent 1200 High Pressure HPLC system with high resolution sub 2 micron particle columns and the full spectral, high scan rate Agilent 6210 TOF system, is the ideal solution for revealing the highest possible number of compounds in a single experiment.

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Technical Breakout Session # 2 - Environmental, Chemical, Food/Flavours, Forensic and Toxicology

Talk 1: “Mass Spectrometry for Qualification and Quantification”
Michael Zumwalt
Senior Application Scientist

This presentation uses examples in GC/MS and LC/MS(/MS) to position the many choices of mass spectrometers in chemical analysis. Typically, an analyst’s challenge is to find all the target compounds and measure the amounts quickly and efficiently, sometimes from complex matrices. It’s not practical to analyze all the target compounds using one universal method. What instruments are better suited for quantitation or for qualification will be described.

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Talk 2: “ Introducing the Agilent 6410 Triple Quadrupole Mass Spectrometer”
Paul Zavitsanos
Product Marketing Manager

The Triple Quadruple (QQQ) is a bench top instrument for MS/MS quantitation in forensics, environmental, food and other applications with challenging matrices. It combines unsurpassed reliability with femtogram level sensitivity at 20-30% less than comparable competitive products. It includes productivity enhancements such as an Autotune function that dramatically enhances reliability and ease-of use.

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Talk 3: “Rapid Analysis of Drugs of Abuse in Oral Fluids by LC/MS/MS”
Michael Zumwalt
Senior Application Scientist

In this work the presence of THC, cocaine, amphetamine, methamphetamine, and MDMA in extracted oral fluid samples is confirmed and quantitated using liquid-phase chromatography interfaced with a triple quadrupole mass spectrometer (LC/MS/MS). Elution times are under 4.5 minutes for the THC, and under 1.5 minutes for the remaining drug compounds. SAMHSA sensitivity requirements are easily met.

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Talk 4: "Analyzing Pharmaceuticals and Herbicides in Surface Water"

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